Why HbA1c Can Lie in Thalassemia Kids
Estimation of HbA1c Levels in Transfusion-Dependent Thalassemia Patients in Comparison With Normal Healthy Individuals
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study checks if a common diabetes test (HbA1c) works well in kids with a blood disease called thalassemia who need blood transfusions.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
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Max 72Case-Control Studies
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Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study checks if a common diabetes test (HbA1c) works well in kids with a blood disease called thalassemia who need blood transfusions.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 543 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Bhatti PK, Ghay R, Singh Narang G, Thaman V, Narang S
Related Content
Claims (6)
If your red blood cells live longer or shorter than average, your A1C test might not give a true picture of your average blood sugar levels.
People with a serious blood disorder called thalassemia who need regular blood transfusions have about the same fasting blood sugar as healthy people, even though their long-term blood sugar marker (HbA1c) is high.
In people with a blood disorder called thalassemia who need regular blood transfusions, their long-term blood sugar marker (HbA1c) goes up when their daily fasting sugar goes up — so even though their HbA1c is usually high, it still gives some clue about their blood sugar changes.
People with a blood disorder called thalassemia who need regular blood transfusions often show high blood sugar on HbA1c tests, but their actual blood sugar is normal—so the test might be giving false alarms in these patients.
Older people with a blood condition called thalassemia who need regular blood transfusions tend to have higher HbA1c levels — a number often linked to blood sugar — even if their actual blood sugar isn't high.