When scientists looked at ALL the studies, they found no proof that bad cholesterol causes heart disease.
Scientific Claim
A comprehensive meta-analysis of epidemiological evidence concludes that LDL cholesterol does not satisfy the Bradford Hill criteria for causality in the development of cardiovascular disease.
Original Statement
“In this study here, they looked at all the different associations done across people of all ages. They didn't cherrypick studies or exclude data that didn't support the narrative. They conducted a comprehensive review of all of the data. Here is what they found. Our search for falsifications of the cholesterol hypothesis confirms that is unable to satisfy any of the Bradford Hill criteria for causality. In fact, the study was titled LDL cholesterol does not cause cardiovascular disease, a comprehensive review of the current literature.”
Context Details
Domain
cardiology
Population
human
Subject
LDL cholesterol
Action
does not satisfy
Target
Bradford Hill criteria for causality in cardiovascular disease
Intervention Details
Evidence from Studies
Supporting (1)
This study says that high LDL cholesterol doesn’t actually cause heart disease, because the evidence doesn’t hold up under scientific rules for proving cause-and-effect—and the people who say it does are ignoring bad data.
Contradicting (2)
The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials
This study shows that lowering 'bad' cholesterol with statins reduces heart attacks and strokes—even in people at low risk—proving that cholesterol directly causes heart disease, not the other way around.
Safety and efficacy of very low LDL-cholesterol intensive lowering: a meta-analysis and meta-regression of randomized trials.
This study shows that lowering LDL cholesterol significantly reduces heart attacks and strokes, with no harmful side effects, which means LDL cholesterol likely causes heart disease—not the other way around.