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Strong Opposition

When scientists looked at ALL the studies, they found no proof that bad cholesterol causes heart disease.

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Pro
59
Against

Evidence from Studies

Supporting (1)

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LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature

2018 Oct

This study says that high LDL cholesterol doesn’t actually cause heart disease, because the evidence doesn’t hold up under scientific rules for proving cause-and-effect—and the people who say it does are ignoring bad data.

Contradicting (1)

59

Community contributions welcome

59

Safety and efficacy of very low LDL-cholesterol intensive lowering: a meta-analysis and meta-regression of randomized trials.

Systematic Review With Meta-Analysis
Human
2023 Feb 2

This study shows that lowering LDL cholesterol significantly reduces heart attacks and strokes, with no harmful side effects, which means LDL cholesterol likely causes heart disease—not the other way around.

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