In mice, a special drug called SCH58261, given daily for four days, works just as well as coffee to protect the brain from memory problems caused by a harmful protein.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice.

Cohort Study

Animal

2007 Jan

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice.

Score: 7

DOI: 10.1016/J.EXPNEUROL.2006.08.008

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