The Claim
In isolated frog skeletal muscle membranes, insulin stimulates (Na+ + K+)-ATPase activity, and this stimulation is completely inhibited by 10⁻³ M ouabain, demonstrating that insulin's effect is specific to the ouabain-sensitive component of (Na+ + K+)-ATPase rather than non-specific ATPase activity.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Insulin boosts a specific cellular pump in frog muscle cells, but this boost gets completely stopped by a chemical called ouabain — meaning insulin only affects that particular pump, not others.
See the scientific wording
The stimulatory effect of insulin on (Na+ + K+)-ATPase in isolated frog skeletal muscle membranes is completely blocked by ouabain at 10⁻³ M, indicating that insulin's action is specific to the ouabain-sensitive (Na+ + K+)-ATPase component rather than non-specific ATPase activity.
What the research says
1 studyStudy: Effect of insulin upon membrane‐bound (Na+ + K+)‐ATPase extracted from frog skeletal muscle.
The study shows that insulin boosts a specific cell pump in frog muscle, and this boost is completely stopped by a blocker called ouabain, meaning insulin works only on that specific pump.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
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