mechanistic
Analysis v1
Strong Support
Insulin boosts a specific cellular pump in frog muscle cells, but this boost gets completely stopped by a chemical called ouabain — meaning insulin only affects that particular pump, not others.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
10
Effect of insulin upon membrane‐bound (Na+ + K+)‐ATPase extracted from frog skeletal muscle.
Cross-Sectional Study
Animal
1975 OctThe study shows that insulin boosts a specific cell pump in frog muscle, and this boost is completely stopped by a blocker called ouabain, meaning insulin works only on that specific pump.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.