A high-fat diet increases inflammation in the testicles of rats, and quercetin reduces this inflammation, which may help protect sperm production and hormone synthesis.

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Supporting (1)

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Quercetin-mediated restoration of high-fat diet-induced male reproductive dysfunction through modifying spermatogenesis and unraveling 3β-HSD, 17β-HSD, and StAR pathways

Cohort Study

Animal

2025 Apr 22

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No contradicting evidence found

Source Study

Quercetin-mediated restoration of high-fat diet-induced male reproductive dysfunction through modifying spermatogenesis and unraveling 3β-HSD, 17β-HSD, and StAR pathways

Score: 9

DOI: 10.1186/s40360-025-00918-y