A high-fat diet lowers the testicles’ natural defenses against cellular damage and increases harmful oxidative byproducts in rats, and quercetin helps restore those defenses and reduce the damage.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Quercetin-mediated restoration of high-fat diet-induced male reproductive dysfunction through modifying spermatogenesis and unraveling 3β-HSD, 17β-HSD, and StAR pathways

Cohort Study

Animal

2025 Apr 22

Contradicting (0)

Community contributions welcome

No contradicting evidence found

Source Study

Quercetin-mediated restoration of high-fat diet-induced male reproductive dysfunction through modifying spermatogenesis and unraveling 3β-HSD, 17β-HSD, and StAR pathways

Score: 9

DOI: 10.1186/s40360-025-00918-y