Strong Support
mechanistic
A protein called βII-spectrin, normally found inside kidney cells, is abnormally exposed on the surface of mesangial cells in people with IgA nephropathy, allowing immune antibodies to bind directly...
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
32
Identification of IgA autoantibodies targeting mesangial cells redefines the pathogenesis of IgA nephropathy
Case-Control Study
Human & Animal & In Vitro
2023 Mar 22Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.