The Claim

A genetic risk score composed of 10 variants associated with parental attained age is significantly associated with longer parental survival in two independent US cohorts (Health and Retirement Study and Wisconsin Longitudinal Study) and with increased odds of having a centenarian parent in the UK Biobank, where each standard deviation increase in the score corresponds to a 19.3% higher odds of having a parent who lived to 100 years or older.

Source: Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
44score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

If someone has a higher genetic score based on 10 specific DNA variants, they're more likely to have a parent who lived to 100 or beyond — each step up in the score means about a 19% better chance of having a centenarian parent.

See the scientific wording

A genetic risk score composed of 10 variants associated with parental attained age is significantly associated with longer parental survival in two independent US cohorts (HRS and WLS) and with having a centenarian parent in the UK Biobank, with each standard deviation increase in the score linked to a 19.3% higher odds of having a centenarian parent.

What the research says

1 study
  1. Study: Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

    The study looked at a genetic score linked to how long parents live and found it really does predict if someone will have a parent who lives to 100, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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