The Claim

A dose of 0.08 g/kg body weight of whey protein hydrolysate activates mTORC1 signaling in skeletal muscle, as evidenced by increased phosphorylation of S6K1 and rpS6, to a similar extent as intact whey protein in healthy young men.

Source: Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In healthy young men, consuming 0.08 grams of whey protein hydrolysate per kilogram of body weight increases phosphorylation of S6K1 and rpS6 proteins in skeletal muscle to the same degree as intact whey protein.

See the scientific wording

A dose of 0.08 g/kg body weight of whey protein hydrolysate activates mTORC1 signaling in skeletal muscle, as evidenced by increased phosphorylation of S6K1 and rpS6, to a similar extent as intact whey protein in healthy young men.

Why this might work

When whey protein hydrolysate is consumed, it breaks down quickly into small pieces that enter muscle cells faster than whole protein. This raises the level of leucine inside the muscle cells, which directly turns on a molecular switch called mTORC1. Once activated, mTORC1 triggers a chain reaction that builds new muscle proteins by increasing the activity of ribosomes and other tools that make proteins.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial.

    The study found that a small amount of broken-down whey protein and regular whey protein both turned on the same muscle-building signal in young men, and they worked just as well as each other.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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