mechanistic
Analysis v1
Strong Support
A person with cataracts had a rare gene change that might make it harder for their cells to take in creatine, based on lab tests.
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0
Evidence from Studies
Supporting (1)
6
Community contributions welcome
6
The cataract and glucosuria associated monocarboxylate transporter MCT12 is a new creatine transporter.
Cross-Sectional Study
Animal
2013 Aug 15The study looked at a specific genetic change found in a person with cataracts and found it makes a protein less able to carry creatine, which matches what the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.