Giving a traditional herbal remedy called Jiao-tai-wan to sleep-deprived rats helps them gain less weight, eat less, and become more sensitive to insulin, while also calming down body-wide inflammation — and this might be because it boosts certain body clock genes in key organs.

A traditional herbal remedy called Jiao-tai-wan may help calm down inflammation in sleep-deprived rats by lowering certain body chemicals and turning down a key inflammation switch in their brain, liver, and fat tissue.

A traditional Chinese medicine called Jiao-tai-wan might help rats that don't get enough sleep process sugar better, by lowering certain blood markers and activating helpful pathways in their body.

When rats don’t get enough sleep, certain genes in their brain called Cry1 and Cry2 become more active, and this seems to calm down inflammation while improving how their body responds to insulin — like a hidden connection between sleep, body clocks, and metabolism.

When rats don't get enough sleep over a long time, their bodies show signs of inflammation and trouble managing blood sugar, but giving them a traditional herbal remedy called Jiao-tai-wan seems to help reduce these problems.