Acetic acid might help lower fat buildup in rat liver cells grown in a lab, especially when used at certain amounts for 6 hours.

Acetic acid helps reduce fat buildup in rat liver cells, and this only happens when a specific energy-sensing pathway (AMPK) is working — if you block that pathway, the effect goes away.

Acetic acid helps liver cells burn fat and stop making too much fat, but only if a key switch in the cell called AMPKα is turned on. If that switch is blocked, acetic acid doesn’t work anymore.

Acetic acid helps the liver burn fat and stop making new fat at the same time.

Acetic acid might help liver cells burn fat better by turning on certain fat-burning genes, especially when used at a specific amount in lab studies.

In cow liver cells, a chemical called acetate seems to help reduce fat buildup, especially when more is used, and this effect goes away if a specific cellular switch (AMPK) is turned off.