When cow liver cells are exposed to certain levels of sodium acetate, it seems to turn down the activity of genes involved in making fat, which might mean less fat is produced in those cells.

11

Pro

0

Against

Evidence from Studies

Supporting (1)

11

Community contributions welcome

11

Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes

Cross-Sectional Study

Animal

2013

The study shows that treating cow liver cells with sodium acetate reduces the activity of key genes that make fat, which matches the claim.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes

Score: 11

DOI: 10.1371/journal.pone.0067880

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When cow liver cells are exposed to certain levels of sodium acetate, it seems to turn down the activity of genes involved in making fat, which might mean the cells make less fat.

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In cow liver cells, a certain amount of a chemical called sodium acetate seems to turn off a key fat-making enzyme, and this might be controlled by another switch called AMPK.

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