Adults aged 50 and older who received the recombinant shingles vaccine had a lower rate of dementia diagnosis over three and five years compared to those who received the older live shingles vaccine,...

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Against

Evidence from Studies

Supporting (1)

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Recombinant zoster vaccine and reduced risk of dementia: matched‐cohort study using large‐scale electronic health records and machine learning methodology

Cohort Study

Human

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Recombinant zoster vaccine and reduced risk of dementia: matched‐cohort study using large‐scale electronic health records and machine learning methodology

Score: 50

DOI: 10.1002/alz.088064