correlational
Analysis v1
Strong Support
Taking melatonin for sleep over a long period might actually increase the risk of heart failure in adults who have insomnia. Instead of being completely safe for the heart, the claim suggests it could raise the chances of developing heart problems by nearly 2% over five years.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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This large study found that people with insomnia who took melatonin long-term were nearly twice as likely to develop heart failure over five years compared to those who didn't take it.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.