correlational
Analysis v1
Strong Support

Taking melatonin for sleep over a long period might actually increase the risk of heart failure in adults who have insomnia. Instead of being completely safe for the heart, the claim suggests it could raise the chances of developing heart problems by nearly 2% over five years.

59
Pro
0
Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

This large study found that people with insomnia who took melatonin long-term were nearly twice as likely to develop heart failure over five years compared to those who didn't take it.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Does long-term melatonin use increase heart failure risk in adults with insomnia? | Scientific Fact Check | Fit Body Science