Adults with or at risk of metabolic syndrome who eat more black beans, Ormosia, and soybean have lower insulin levels and less insulin resistance.
Mechanism
Synthesis from 1 study
Black beans, Ormosia, and soybeans feed gut bacteria that make butyrate. Butyrate seals the gut lining and stops inflammation from spreading. This lets insulin work better, lowering blood sugar and insulin levels.
Most probable mechanism
Eating black beans, Ormosia, and soybeans feeds good bacteria in the gut that make butyrate. Butyrate strengthens the gut lining and stops inflammation from spreading through the body. This allows the body to respond better to insulin, lowering blood sugar and insulin levels.
Dietary fibers and polyphenols from black beans, Ormosia, and soybean are fermented by specific gut microbial guilds that produce butyrate
Butyrate serves as an energy source for colon cells and inhibits histone deacetylases, enhancing intestinal barrier integrity
Improved intestinal barrier function reduces translocation of microbial components into systemic circulation, suppressing activation of NF-κB and pro-inflammatory cytokine production
Reduced systemic inflammation enhances insulin receptor signaling in skeletal muscle, liver, and adipose tissue
Genetic variation in a butyrate-synthesis pathway modulates the magnitude of insulin sensitivity improvement following legume consumption
Evidence from Studies
Supporting (1)
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Contradicting (0)
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