Doing 10 weeks of leg exercises that strengthen your knee muscles boosts one specific hormone receptor in your muscles (ERα), but doesn’t change two others (AR and ERβ).

31

Pro

0

Against

Evidence from Studies

Supporting (1)

31

Community contributions welcome

31

Influence of intramuscular steroid receptor content and fiber capillarization on skeletal muscle hypertrophy

Cross-Sectional Study

Human

2024 Jun

The study looked at the same type of exercise and people described in the claim, and found that it increased one type of estrogen receptor in muscles, but not the others, just like the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Influence of intramuscular steroid receptor content and fiber capillarization on skeletal muscle hypertrophy

Score: 31

DOI: 10.1111/sms.14668

Similar Assertions

People new to weight training who have more of a certain protein in their muscles (called ERα) tend to gain more muscle size after 10 weeks of leg exercises — so this protein might help explain why some people build muscle faster than others.

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