After 20 days of intense interval training, the baseline levels of the METRNL gene in muscle rise significantly, suggesting the muscle adapts to repeated high-intensity exercise by increasing this...

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Impact of a single bout of high-intensity interval exercise and short-term interval training on interleukin-6, FNDC5, and METRNL mRNA expression in human skeletal muscle

Randomized Controlled Trial

Human

2018 Apr

Contradicting (0)

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Impact of a single bout of high-intensity interval exercise and short-term interval training on interleukin-6, FNDC5, and METRNL mRNA expression in human skeletal muscle

Score: 31

DOI: 10.1016/j.jshs.2017.01.003