The Claim
In previously untrained young men, eight weeks of unilateral resistance training increases resting mixed muscle protein synthesis rates by 48% compared to untrained limbs, while myofibrillar protein synthesis remains unchanged at rest, indicating divergent regulation of protein subfractions following training.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When young men who haven't trained before do one-arm exercises for eight weeks, their resting muscle building speed goes up by almost half in that arm, but the part that builds muscle fibers stays the same, showing different parts of muscle react differently to exercise.
See the scientific wording
Eight weeks of unilateral resistance training in previously untrained young men increases resting mixed muscle protein synthesis rates by 48% compared to untrained limbs, while myofibrillar protein synthesis remains unchanged at rest, indicating divergent regulation of protein subfractions following training.
What the research says
1 studyStudy: Fasted‐state skeletal muscle protein synthesis after resistance exercise is altered with training
The study did exactly what the claim described—training one leg for eight weeks—and found that protein building at rest went up overall but not for the specific muscle-building proteins, just like the claim said.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.