When you exercise, your muscles make a protein called TSC1 stick to the internal skeleton of the cell, and at the same time, they turn on another protein system called mTORC1 that helps the cell grow.

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Against

Evidence from Studies

Supporting (1)

20

Community contributions welcome

20

The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.

Cross-Sectional Study

Human

2017 Jan

When you exercise, a protein called TSC1 moves to the muscle’s structural framework, and this lets another system (mTORC1) in the muscle fluid turn on to help build proteins — exactly what the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.

Score: 20

DOI: 10.1016/j.bbamcr.2016.10.007

Similar Assertions

When you lift weights, your muscles turn on a specific molecular switch called mTORC1, which helps build more muscle protein. But just because this switch flips on right after a workout doesn’t mean you’ll definitely get bigger muscles over time—it doesn’t always line up.

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