When you exercise, your muscles make a protein called TSC1 stick to the internal skeleton of the cell, and at the same time, they turn on another protein system called mTORC1 that helps the cell grow.

From: The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.

Strongly supported

Multiple high-quality studies back this claim.

20
Pro
0
Against
mechanistic
1 study

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What this claim means

When you exercise, your muscles make a protein called TSC1 stick to the internal skeleton of the cell, and at the same time, they turn on another protein system called mTORC1 that helps the cell grow.

See the technical phrasing

In human muscle tissue, exercise causes TSC1 to associate with the cytoskeleton and simultaneously activates mTORC1 in the cytoplasm.

What the research says

Supports

1 study

20

Study: The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.

This study provides evidence supporting the claim.

Contradicts

0 studies

0

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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