mechanistic
Analysis v1
Strong Opposition
After a really tough bike ride, young guys can lose about half a kilo of 'lean mass' the next day if they don’t eat enough carbs to refuel — but it’s not muscle loss, it’s mostly water stuck to stored fuel in the body.
0
45
Evidence from Studies
Supporting (0)
0
Community contributions welcome
No supporting evidence found
Contradicting (1)
45
Community contributions welcome
45
Muscle glycogen depletion does not alter segmental extracellular and intracellular water distribution measured using bioimpedance spectroscopy.
Randomized Controlled Trial
Human
2018 Jun 1The study found that fat-free mass went down after hard exercise without carb recovery, but the water in muscles didn’t change like we’d expect if glycogen and its water were the main reason.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.