The Claim

In trained cyclists, post-exercise carbohydrate-protein supplementation reduces glycogen synthase phosphorylation by 3-fold more than placebo within 45 minutes of recovery, indicating greater activation of glycogen synthase and a stronger signal for muscle glycogen replenishment.

Source: Post exercise carbohydrate–protein supplementation: phosphorylation of muscle proteins involved in glycogen synthesis and protein translation

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
46score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In trained cyclists, consuming a carbohydrate-protein drink after exercise causes a threefold greater reduction in glycogen synthase phosphorylation compared to a placebo within 45 minutes of recovery, resulting in higher glycogen synthase activity and increased muscle glycogen replenishment.

See the scientific wording

In trained cyclists, post-exercise carbohydrate-protein supplementation reduces glycogen synthase phosphorylation by 3-fold more than placebo within 45 minutes of recovery, indicating greater activation of glycogen synthase and a stronger signal for muscle glycogen replenishment.

Why this might work

After exercise, consuming sugar and protein raises blood insulin and amino acid levels, which turn on a signaling chain that shuts off a brake on the glycogen-building enzyme. This allows the enzyme to switch on fully and rapidly rebuild muscle glycogen stores.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Post exercise carbohydrate–protein supplementation: phosphorylation of muscle proteins involved in glycogen synthesis and protein translation

    After cycling hard, drinking a sugar-and-protein shake turned on the muscle's glycogen-rebuilding enzyme much more than drinking water, helping muscles recover faster.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.