The Claim
In untrained men, resistance exercise does not significantly alter ERK1/2 phosphorylation 30 minutes post-exercise, regardless of training volume, indicating that this signaling pathway is not acutely involved in the volume-dependent anabolic signaling response to resistance training under fasted conditions.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
For guys who don’t lift regularly, doing weight exercises doesn’t change a specific body signal (ERK1/2) 30 minutes after working out, no matter how hard or long they train — so this signal probably isn’t what tells their muscles to grow right after a fasted workout.
See the scientific wording
In untrained men, resistance exercise does not significantly alter ERK1/2 phosphorylation 30 minutes post-exercise, regardless of training volume, suggesting this pathway is not acutely involved in the volume-dependent anabolic signaling response to resistance training in a fasted state.
What the research says
1 studyThe study found that after lifting weights, a key protein signal called ERK1/2 didn’t change at all in untrained men, no matter how many sets they did — which matches the claim that this signal isn’t involved in how muscle growth responds to more exercise.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.