mechanistic
Analysis v1
Strong Support
After losing a large amount of weight, the body continues to burn fewer calories at rest than expected based on its new size, and this persistent reduction in energy expenditure may make it harder to keep the weight off over time.
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Evidence from Studies
Supporting (1)
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About Unsuccessful Responders to Diet and Physical Activity Interventions: A Focus on Energy Balance and Body-Weight Loss
Narrative Review
Human
2026 Jan 7Some people lose weight but their bodies slow down metabolism more than expected, making it harder to keep the weight off—even if they eat right and exercise. This study shows that this happens to some people due to how their bodies naturally respond, not because they’re not trying.
Contradicting (0)
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No contradicting evidence found
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