The Claim

Following weight loss in obese adult women, ghrelin levels increase significantly and leptin levels decrease, and these hormonal changes are not correlated with self-reported hunger.

Source: The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
38score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

After losing weight, obese adult women experience a rise in ghrelin and a drop in leptin, but these changes do not match their reported feelings of hunger.

See the scientific wording

After weight loss in obese adult women, ghrelin levels increase significantly while leptin levels decrease, consistent with a physiological drive to restore body weight, but these changes do not correlate with self-reported hunger.

Why this might work

After losing weight, the stomach produces more of a hormone that signals hunger, and fat tissue produces less of a hormone that signals fullness. These changes activate brain circuits that increase appetite and slow down calorie burning, but the person does not feel hungrier than before.

Verified mechanismbased on 1 study

What the research says

1 study

  1. Study: The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study

    After losing weight, these women’s bodies made more of the hunger hormone and less of the fullness hormone—just like the claim says—but they didn’t feel hungrier than before. So their bodies were trying to make them eat more, but they didn’t notice it.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.