The Claim

After resistance training, whole body protein turnover increased by approximately 10% in younger individuals but remained unchanged in older individuals, while myofibrillar proteolysis, as measured by urinary 3-methylhistidine excretion, showed no change in either group.

Source: Myofibrillar protein synthesis in young and old human subjects after three months of resistance training.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
37score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

After resistance training, younger people experienced a 10% increase in overall protein turnover, while older people did not. The rate of muscle breakdown, measured by a specific urinary marker, did not change in either group.

See the scientific wording

Whole body protein turnover increased by approximately 10% only in the younger group after resistance training, while myofibrillar proteolysis, measured by urinary 3-methylhistidine excretion, was unchanged in both groups, suggesting differential systemic metabolic responses to training by age.

Why this might work

After lifting weights, younger people's muscles send stronger signals to activate protein building throughout the body, which increases overall protein use. Older people's muscles do not send these signals as strongly, so their bodies do not increase overall protein use, even though muscle breakdown stays the same in both groups.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Myofibrillar protein synthesis in young and old human subjects after three months of resistance training.

    After lifting weights, younger people’s bodies started using protein more actively overall, but older people’s didn’t — and neither group broke down more muscle, as shown by urine tests. This suggests aging changes how the body reacts to exercise.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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