mechanistic
Analysis v3
After sun exposure, a chemical tag (phosphate) is added to a protein called MITF, making it stop making pigment and instead team up with other proteins to fix DNA damage.
Evidence from Studies
Supporting (1)
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Community contributions welcome
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ATM signaling delays skin pigmentation upon UV exposure by mediating MITF function towards DNA repair mode.
Computational/Algorithm Study
Human & Animal
2023 DecContradicting (0)
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Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.