After taking the supplement for 6 months, blood sugar responses after meals stayed stable, while they got worse in people who didn't take it.
Scientific Claim
Long-term supplementation with inulin-propionate ester was associated with prevention of deterioration in postprandial glucose response, with no significant change in AUC0-300 min (1630 to 1630 min×mmol/L, p=0.993) compared to deterioration in the control group (1600 to 1691 min×mmol/L, p=0.010).
Source Excerpt
“The change in postprandial glucose AUC to the standardised breakfast at week 24 was significantly different between groups (see online supplementary figure S6; p=0.037). Glycaemic response significantly deteriorated following inulin-control supplementation (AUC0–300 min 1600 min×mmol/L (95% CI 1495 to 1705) to 1691 min×mmol/L (95% CI 1580 to 1802), p=0.010) but remained unchanged following inulin-propionate ester supplementation (AUC0–300 min 1630 min×mmol/L (95% CI 1534 to 1727) to 1630 min×mmol/L (95% CI 1543 to 1717), p=0.993), in keeping with the differences in weight gain and body fat distribution observed within the groups.”
Evidence from Studies
Supporting Studies
Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
The study measured postprandial glucose response and found a significant difference between groups, with the intervention group maintaining stable glucose response while the control group showed deterioration. The randomised controlled design allows for comparison between intervention and control groups.