Back to Study: Effects of targeted delivery of propionate to the ...
quantitative
positive effect

After taking the supplement for 6 months, people tended to eat less food at meals, but this difference wasn't quite statistically significant.

Scientific Claim

Long-term supplementation with inulin-propionate ester was associated with a trend toward reduced food intake (8.7%) compared to control, though this did not reach statistical significance (p=0.100).

Source Excerpt

The change in food intake at an ad libitum meal following 24 weeks of supplementation was not statistically significant between groups (p=0.972), though long-term inulin-propionate ester intake showed a trend towards a lower food intake by 8.7% from 836 kcal (95% CI 724 to 948) to 763 kcal (95% CI 654 to 872) (p=0.100).

Evidence from Studies

Supporting Studies

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

RCT
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58%
Evidence Assessment
Supported

The study measured food intake at an ad libitum meal after 24 weeks and found a non-significant trend toward reduced intake in the intervention group. The randomised controlled design allows for comparison between intervention and control groups.