Back to Study: Effects of targeted delivery of propionate to the ...
quantitative
positive effect

People who took the supplement for 6 months had slightly lower total cholesterol levels than those who didn't take it.

Scientific Claim

Inulin-propionate ester supplementation was associated with a significant reduction in fasting total cholesterol levels compared to control, with reductions of 0.39 mmol/L in the intervention group versus 0.30 mmol/L in the control group.

Source Excerpt

Inulin-propionate ester and inulin-control supplementation significantly reduced circulating levels of total cholesterol, high-density lipoprotein, alanine transaminase and alkaline phosphatase (table 1). Significant reductions in low-density lipoprotein (p<0.001) and aspartate transaminase (p=0.007) were only observed within the propionate ester group.

Evidence from Studies

Supporting Studies

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

RCT
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58%
Evidence Assessment
Supported

The study measured blood lipid levels and found significant reductions in total cholesterol in both groups, with additional reductions in LDL and AST specifically in the intervention group. The randomised controlled design allows for comparison between intervention and control groups.