Back to Study: Effects of targeted delivery of propionate to the ...
quantitative
positive effect

Taking a special fiber supplement for 6 months helped overweight people gain less weight than those who didn't take it, with much fewer people gaining a significant amount of weight.

Scientific Claim

Supplementing with 10g/day of inulin-propionate ester for 24 weeks significantly reduced weight gain in overweight adults, with only 4% of participants gaining ≥3% of baseline body weight compared to 25% in the control group.

Source Excerpt

One of 25 participants gained ≥3% of their baseline body weight following inulin-propionate ester supplementation (4%), as compared with 6 of 24 participants (25%) in the inulin-control group (figure 3A, p=0.036).

Evidence from Studies

Supporting Studies

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

RCT
View study →
58%
Evidence Assessment
Supported

The study directly compared weight gain between groups over 24 weeks, showing a statistically significant difference in the proportion of participants gaining ≥3% body weight. The randomised controlled design allows for comparison between intervention and control groups.