For people with fatty liver disease, taking the supplement for 6 months reduced the amount of fat in their liver.
Scientific Claim
In overweight adults with non-alcoholic fatty liver disease (NAFLD), 24 weeks of 10g/day inulin-propionate ester supplementation significantly reduced intrahepatocellular lipid content from 22.1% to 15.9% (p=0.038).
Source Excerpt
“Subjects meeting the baseline diagnostic criteria for non-alcoholic fatty liver disease (NAFLD) (IHCL >5.5%) had a significant reduction in IHCL content following inulin-propionate ester supplementation (22.1% (95% CI 7.7 to 36.6) to 15.9% (95% CI 5.2 to 26.5), p=0.038, n=11; figure 3B).”
Evidence from Studies
Supporting Studies
Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
The study specifically measured liver fat content in participants with NAFLD and found a statistically significant reduction in the intervention group compared to control. The randomised controlled design allows for comparison between intervention and control groups.