Back to Study: Effects of targeted delivery of propionate to the ...
quantitative
negative effect

People who took the control supplement reported more gas and bloating than those who took the propionate supplement.

Scientific Claim

Inulin-propionate ester supplementation was associated with significantly greater ratings of flatulence in the control group compared to the intervention group (p=0.004).

Source Excerpt

Ratings of nausea were not different between supplementation groups (p=0.736), though there were significantly greater ratings of flatulence (p=0.004) in the inulin-control group during the supplementation period compared with the inulin-propionate ester group (see online supplementary table S1).

Evidence from Studies

Supporting Studies

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

RCT
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58%
Evidence Assessment
Supported

The study measured gastrointestinal side effects and found a statistically significant difference in flatulence ratings between groups, with higher ratings in the control group. The randomised controlled design allows for comparison between intervention and control groups.