The Claim
Chronic resistance exercise in rats is associated with increased IRS1 (2.7-fold) and total Akt (59%) protein levels in muscle, suggesting that upregulation of upstream insulin signaling components may compensate for reduced mTORC1 activity to support protein synthesis.
What the research says
Not yet evaluated
We are still looking at what the research says.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When rats do regular strength training, their muscles show higher levels of certain proteins that help with insulin signaling. This might help their muscles build protein even when another important pathway isn't as active.
See the scientific wording
Chronic resistance exercise in rats is associated with increased IRS1 (2.7-fold) and total Akt (59%) protein levels in muscle, suggesting upregulation of upstream insulin signaling components may compensate for reduced mTORC1 activity to support protein synthesis.
Score breakdown, mechanism chain, raw evidence, ideal studies needed
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.