As we get older, levels of a molecule called NAD+ in our skin go down, which slows down important repair processes and makes skin heal slower and break down over time.

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Evidence from Studies

Supporting (1)

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The Mitochondrial Blueprint of Skin Aging: From Damage Signals to Dermatologic Interventions.

Narrative Review

2026 Mar 4

The study explains that as skin ages, it loses NAD+, which affects cell energy and repair systems, matching the main idea of the claim.

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The Mitochondrial Blueprint of Skin Aging: From Damage Signals to Dermatologic Interventions.

Score: 1

DOI: 10.14336/AD.2025.1585

Similar Assertions

Using certain supplements like NMN or nicotinamide riboside might help older skin stay healthier by boosting cell energy, reducing damage, and increasing collagen — the stuff that keeps skin firm.

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