The Claim

Eight-week administration of Ashwagandha root extract (ARE) at a dose of 600 mg/day is not associated with clinically significant changes in renal function, as measured by serum creatinine, in adults with stress and anxiety. Serum creatinine levels remain within normal range and are comparable to placebo.

Source: Safety of 8-Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi-Center, Double-Blinded, Placebo-Controlled Study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
80score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Taking Ashwagandha root extract (600 mg per day for 8 weeks) does not cause any meaningful changes in kidney function in adults with stress and anxiety. Kidney function, measured by a blood test called serum creatinine, stays normal and is the same as in people taking a placebo.

See the scientific wording

Eight-week administration of Ashwagandha root extract (ARE) 600 mg/day is not associated with clinically significant changes in renal function as measured by serum creatinine in adults with stress and anxiety, with levels remaining within normal range and comparable to placebo.

Why this might work

The kidneys normally filter waste like creatinine from the blood. Taking Ashwagandha root extract for 8 weeks does not change how the kidneys work, so creatinine levels stay normal and the same as if you took a sugar pill.

Hypothetical mechanismbased on 1 study

What the research says

1 study
  1. Study: Safety of 8-Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi-Center, Double-Blinded, Placebo-Controlled Study.

    The study gave people 600 mg of ashwagandha or a fake pill every day for 8 weeks and checked their kidney function with blood tests. Their kidney markers stayed normal and were the same in both groups, showing ashwagandha doesn't hurt the kidneys.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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