The Claim
Physiological concentrations of erythritol (≥18 μM) enhance platelet aggregation and activation in response to adenosine diphosphate and thrombin receptor agonists in human platelet-rich plasma and isolated platelets, an effect not observed with glucose or 1,5-anhydroglucitol.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
At normal levels found in the human body, erythritol increases platelet activity when exposed to adenosine diphosphate and thrombin receptor agonists, while glucose and 1,5-anhydroglucitol do not produce this effect.
See the scientific wording
Physiological concentrations of erythritol (≥18 μM) enhance platelet aggregation and activation in response to adenosine diphosphate and thrombin receptor agonists in human platelet-rich plasma and isolated platelets, an effect not observed with glucose or 1,5-anhydroglucitol, suggesting a specific pro-thrombotic mechanism.
When erythritol enters the blood at normal levels after eating, it makes platelets more sensitive to clotting signals. This causes more calcium to flood inside platelets, which turns on proteins that make platelets sticky and cause them to clump together faster, forming clots more quickly under blood flow.
What the research says
1 studyStudy: The artificial sweetener erythritol and cardiovascular event risk
After people eat foods with erythritol, their blood levels of this sweetener rise enough to make their blood platelets more likely to clump together and form dangerous clots — something sugar doesn’t do.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.