In people who live to be 100 or older, both inherited traits and lifestyle factors seem to affect their lipoprotein(a) levels, showing that more than just genetics plays a role in these levels for long-lived individuals.

20

Pro

0

Against

Evidence from Studies

Supporting (1)

20

Community contributions welcome

20

Elevated lipoprotein(a) levels and small apo(a) isoforms are compatible with longevity: evidence from a large population of French centenarians.

Cross-Sectional Study

Human

The study looks at why some very old people have high lipoprotein(a) levels and finds that both genes and environment play a part, which matches the claim exactly.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Elevated lipoprotein(a) levels and small apo(a) isoforms are compatible with longevity: evidence from a large population of French centenarians.

Score: 20

DOI: 10.1016/S0021-9150(97)00217-7

Similar Assertions

A certain genetic trait that usually raises heart disease risk doesn't seem to shorten life in very old French people, showing it might not always be bad for living a long life.

20

0

82%

Even though high levels of a certain blood fat called Lp(a) are linked to heart problems in younger people, this study found that very old French people (over 100 years old) can have high Lp(a) and still live long lives.

20

0

82%