The Claim

In untrained adults, performing either single-joint knee extensions or multi-joint leg presses at 70% of one-repetition maximum for 5 sets of 10 repetitions, conducted twice per week over 12 weeks, is associated with comparable hypertrophic gains in the vasti muscles (ranging from 4.4% to 7.2%) and overall quadriceps femoris muscle volume, suggesting both exercise modalities are similarly effective for targeting these muscle groups.

Source: Hypertrophic Effects of Single- versus Multi-Joint Exercise: A Direct Comparison Between Knee Extension and Leg Press.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
44score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

If you're new to working out, doing leg presses or knee extensions twice a week for 12 weeks will grow your thigh muscles about the same amount—so pick the one you like!

See the scientific wording

In untrained adults, both single-joint knee extensions and multi-joint leg presses (70% 1RM, 5 sets of 10 reps, 2 sessions/week for 12 weeks) are associated with similar hypertrophic gains in the vasti muscles (ranging from 4.4% to 7.2%) and overall quadriceps femoris volume, indicating that either modality can effectively target these areas.

What the research says

1 study
  1. Study: Hypertrophic Effects of Single- versus Multi-Joint Exercise: A Direct Comparison Between Knee Extension and Leg Press.

    The study shows that both leg presses and knee extensions work equally well for growing the main parts of the quadriceps muscles in beginners, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.