BPC 157 doesn't just 'balance' nitric oxide - research shows it actually increases nitric oxide production, and we don't know if this could be harmful at higher doses people might take.
Evidence from Studies
No evidence studies found yet.
What Would Prove This
Per GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this claim, ordered from strongest to weakest.
Dose-dependent effects of BPC 157 on NO metabolites, eNOS phosphorylation, and NOS activity in humans
Double-blind RCT in 60 healthy volunteers randomized to placebo, 200 μg, 400 μg, or 800 μg BPC 157 oral dose, with serial measurements of NOx, nitrite, nitrate, eNOS phosphorylation, and L-arginine at baseline and multiple timepoints over 24 hours
NO system modulation in humans across different BPC 157 dose levels and regimens
Prospective cohort study of 200 patients receiving varying BPC 157 doses for different indications, with comprehensive NO pathway biomarker monitoring