Strong Opposition

Taking 2 grams of carnosine every day for about 3 months might help overweight people have lower insulin levels and less insulin resistance, possibly because carnosine helps clean up harmful molecules that mess with how insulin works in the body.

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Pro
33
Against

Evidence from Studies

Supporting (0)

0

Community contributions welcome

No supporting evidence found

Contradicting (1)

33

Community contributions welcome

The study tested carnosine supplements and found they did NOT improve insulin resistance (measured by HOMA-IR), which directly contradicts the claim that carnosine reduces insulin and insulin resistance in overweight individuals.

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.