Too much insulin makes your body's stress system active, speeding up your heart and tightening blood vessels, which raises blood pressure.
Scientific Claim
Chronic elevation of insulin activates the sympathetic nervous system, leading to increased heart rate, cardiac output, and peripheral vasoconstriction, thereby raising blood pressure.
Original Statement
“The second is that chronic insulin elevation activates the sympathetic nervous system which increases your heart rate. It boosts cardiac output and constricts peripheral blood vessels. More output means more resistance and higher pressure.”
Context Details
Domain
cardiology
Population
human
Subject
chronic insulin elevation
Action
activates
Target
sympathetic nervous system leading to increased cardiac output and vasoconstriction
Intervention Details
Evidence from Studies
Supporting (2)
Control of Blood Pressure, Appetite, and Glucose by Leptin in Mice Lacking Leptin Receptors in Proopiomelanocortin Neurons
This study helps understand how the body controls blood pressure and sugar levels, which is related to how insulin affects the nervous system and blood pressure.
This study shows how insulin affects heart function and blood pressure through the nervous system.
Contradicting (2)
This study suggests that long-term insulin use may have negative effects on blood vessels, contradicting the idea that insulin always helps blood pressure.
This study shows that insulin's effects on blood pressure might be more complex than previously thought, involving the kidneys.