Endurance athletes with Parkinson’s disease have lower levels of the protein irisin in their blood than non-athletic individuals with Parkinson’s disease.
See the scientific wording
Chronic, intense physical exercise in endurance athletes with Parkinson’s disease is associated with significantly lower plasma levels of irisin compared to non-athletic individuals with Parkinson’s disease.
Correlational — new studies may shift this
ObservationalOne low-scoring study links this claim to the outcome, but causation is not established.
What the research says
1 study reviewedSupporting (1)
Cross-Sectional StudyHuman2025
People with Parkinson’s who train like marathon runners have less of a protein called irisin in their blood than those with Parkinson’s who don’t exercise much. The study found this difference for sure.
Contradicting (0)
No contradicting studies found yet
That doesn't mean it's settled — it just means no study has tested the opposite.
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Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting study
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