When you're under constant stress, your body uses up too much of a mineral called magnesium, which can mess with your brain's ability to calm down, making you feel more anxious or on edge.

9

Pro

0

Against

Evidence from Studies

Supporting (1)

9

Community contributions welcome

9

Brain glutamic acid decarboxylase-67 kDa alterations induced by magnesium treatment in olfactory bulbectomy and chronic mild stress models in rats

Cohort Study

Animal

2016 Oct

This study showed that giving magnesium to stressed rats helped their brains make more of a calming chemical (GABA), which may help reduce anxiety and overreaction to stress.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Similar Assertions

When rats are stressed out for a long time, giving them a magnesium supplement every day for five weeks boosts a specific brain protein that helps calm the brain, even though the stress itself doesn’t change that protein.

9

0

80%

Giving rats with depression-like symptoms a daily dose of magnesium for a few weeks seems to boost a brain chemical involved in calming nerves, but only in certain brain areas — maybe that’s why they act less depressed.

9

0

75%

In rats with depression-like symptoms, magnesium might help by boosting a brain chemical that calms nerve activity, especially in areas linked to mood.

9

0

74%

Giving magnesium to depressed rats doesn't change the level of a specific brain protein called GAD-67 in a part of the brain called the hippocampus, so magnesium probably isn't working on that protein in that area.

9

0

73%