The Claim

Ingestion of 0.08 g/kg body weight of whey protein hydrolysate stimulates muscle protein synthesis by approximately 43% in healthy young men, with a similar magnitude of effect as intact whey protein, indicating that hydrolysis does not enhance acute anabolic potency at this low dose.

Source: Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Consuming 0.08 grams of whey protein hydrolysate per kilogram of body weight increases muscle protein synthesis by about 43% in healthy young men, and this increase is no greater than that caused by the same amount of intact whey protein.

See the scientific wording

Ingestion of 0.08 g/kg body weight of whey protein hydrolysate stimulates muscle protein synthesis by approximately 43% in healthy young men, with a similar magnitude of effect as intact whey protein, indicating that hydrolysis does not enhance acute anabolic potency at this low dose.

Why this might work

When whey protein is broken down into small pieces, the body absorbs leucine faster, which triggers a molecular signal in muscle cells that turns on the machinery to build new muscle proteins. This signal and the resulting muscle growth are the same whether the whey is broken down or not, as long as the amount of leucine delivered is enough.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial.

    The study found that breaking down whey protein didn't make it better at building muscle than regular whey protein when taken in a small amount — both worked equally well to boost muscle protein synthesis by about 43% in young men.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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