The Claim
Creatine supplementation increases the conversion rate of testosterone to dihydrotestosterone (DHT), as evidenced by a sustained 22% elevation in the DHT-to-testosterone ratio without a change in total testosterone, indicating enhanced 5α-reductase activity in healthy young male athletes.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Creatine supplementation increases the ratio of dihydrotestosterone to testosterone in healthy young male athletes, without changing total testosterone levels, indicating greater activity of the enzyme that converts testosterone to dihydrotestosterone.
See the scientific wording
Creatine supplementation increases the conversion rate of testosterone to dihydrotestosterone (DHT), as inferred from a sustained 22% elevation in the DHT:T ratio without a change in total testosterone, suggesting enhanced 5α-reductase activity in healthy young male athletes.
Creatine increases the activity of an enzyme that turns testosterone into a stronger hormone called dihydrotestosterone, leading to more of this hormone in the blood without changing the amount of testosterone.
What the research says
1 studyThis study found that when young athletes took creatine, their body made more of a stronger hormone called DHT, even though the main hormone (testosterone) didn’t change. This means creatine might be helping the body turn testosterone into DHT more efficiently.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.