Taking 20 grams of creatine a day for a week after a certain kind of stroke might lower a brain-related protein linked to inflammation in older adults — suggesting it could help with brain healing.

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Pro

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Influence of CReatine Supplementation on mUScle Mass and Strength After Stroke (ICaRUS Stroke Trial): A Randomized Controlled Trial

Randomized Controlled Trial

Human

2024 Nov 29

The study gave older stroke patients 20 grams of creatine per day and found their progranulin levels went down, which matches what the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Influence of CReatine Supplementation on mUScle Mass and Strength After Stroke (ICaRUS Stroke Trial): A Randomized Controlled Trial

Score: 47

DOI: 10.3390/nu16234148

Similar Assertions

If older adults who've had a certain kind of stroke take 20 grams of creatine every day for a week, their body shows signs that it's absorbing and using the supplement, based on a rise in a related blood marker.

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47

84%

Older adults who had a stroke didn’t get stronger or gain more muscle from taking creatine for a week, even if they ate enough protein and started moving early.

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78%

Older adults in the hospital for a certain kind of stroke can safely take a specific dose of creatine for a week — it’s generally well-tolerated, though some might get mild stomach issues or temporary changes in a kidney-related blood test.

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75%