The Claim

In older adults during the acute phase of ischemic stroke, 20 g/day of oral creatine supplementation for 7 days significantly reduces serum progranulin levels compared to placebo, indicating a potential mechanism through which creatine may influence neuroinflammatory or tissue repair pathways.

Source: Influence of CReatine Supplementation on mUScle Mass and Strength After Stroke (ICaRUS Stroke Trial): A Randomized Controlled Trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
47score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

Taking 20 grams of creatine a day for a week after a certain kind of stroke might lower a brain-related protein linked to inflammation in older adults — suggesting it could help with brain healing.

See the scientific wording

In older adults during the acute phase of ischemic stroke, 20 g/day of oral creatine supplementation for 7 days significantly reduces serum progranulin levels compared to placebo, suggesting a potential novel biological mechanism by which creatine may modulate neuroinflammation or tissue repair pathways.

What the research says

1 study

  1. Study: Influence of CReatine Supplementation on mUScle Mass and Strength After Stroke (ICaRUS Stroke Trial): A Randomized Controlled Trial

    The study gave older stroke patients 20 grams of creatine per day and found their progranulin levels went down, which matches what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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