The Claim
Creatine uptake mediated by the SLC6A8 transporter increases intracellular osmotic load through sodium co-transport, which results in water influx into the cell and a subsequent increase in intracellular volume.
What the research says
Not yet evaluated
We are still looking at what the research says.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When your cells take in creatine, they also pull in sodium, which makes the inside of the cell saltier. To balance that, water rushes in, making the cell swell up a bit.
See the scientific wording
Creatine uptake via SLC6A8 increases intracellular osmotic load by co-transporting sodium, thereby drawing water into the cell and increasing intracellular volume.
What the research says
1 studyStudy: Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1
The study shows that when cells take in creatine, they also pull in sodium, which makes the inside of the cell more concentrated and naturally pulls water in with it.
Related videos
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.