mechanistic
Analysis v1
When your cells take in creatine, they also pull in sodium, which makes the inside of the cell saltier. To balance that, water rushes in, making the cell swell up a bit.
Evidence from Studies
Supporting (1)
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Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1
Computational/Algorithm Study
In Vitro
2022The study shows that when cells take in creatine, they also pull in sodium, which makes the inside of the cell more concentrated and naturally pulls water in with it.
Contradicting (0)
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.