The Claim

Daily supplementation with 360 micrograms of vitamin K2 over two years results in a smaller increase in arterial calcium mass compared to placebo.

Source: Does Vitamin K2 Actually Protect Your Heart? (New Trial)

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
49score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
2 studies reviewed
In plain English

Taking 360 micrograms of vitamin K2 daily for two years leads to less buildup of calcium in the arteries than taking a placebo.

See the scientific wording

Daily supplementation with 360 micrograms of vitamin K2 over two years results in a smaller increase in arterial calcium mass compared to placebo.

Why this might work

Vitamin K2 enables a protein in artery walls to bind calcium and stop it from forming hard deposits. Without enough vitamin K2, this protein stays inactive and calcium builds up, making arteries stiff. When vitamin K2 is present, it turns on the protein, which grabs calcium and prevents it from turning into rock-like crystals in the artery walls.

Verified mechanismbased on 3 studies

What the research says

2 studies
  1. Study: Beneficial effects of one-year menaquinone-7 supplementation on vascular stiffness and blood pressure in post-menopausal women

    Taking vitamin K2 for a year helped older women’s arteries stay more flexible and less stiff, which means less calcium was likely building up in them. This suggests that taking more for longer (like in the claim) would probably help even more.

  2. Study: #5745 CORRELATION BETWEEN MATRIX GLA PROTEIN LEVEL AND EFFECT OF VITAMIN K2 THERAPY ON VASCULAR CALCIFICATION IN HEMODIALYSIS PATIENTS

    Taking vitamin K2 daily helped reduce calcium buildup in the arteries of sick patients, even though the dose and time were lower than in the claim. This suggests that higher doses for longer might work even better.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 2 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.