quantitative
Analysis v1
Strong Support
Taking astaxanthin supplements (a red-orange antioxidant pigment found in salmon and shrimp) every day for 1-4 months doesn't seem to make wrinkles noticeably shallower in middle-aged people, according to research that combined results from multiple clinical trials.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing
Systematic Review With Meta-Analysis
2021 Aug 24This study tested whether taking astaxanthin pills by mouth helps reduce wrinkles. The results show that astaxanthin did NOT significantly reduce wrinkle depth (the study found the same statistics the claim mentioned: SMD = -0.26, p=0.11). This means the study SUPPORTS the claim that oral astaxanthin doesn't significantly reduce wrinkles.
Contradicting (0)
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.