The Claim
Oral astaxanthin supplementation at doses of 2-12 mg/day for 4-16 weeks does not significantly reduce wrinkle depth in middle-aged adults, as demonstrated by pooled analysis of randomized controlled trials (SMD = -0.26, 95% CI: -0.58 to 0.06, p=0.11).
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking astaxanthin supplements (a red-orange antioxidant pigment found in salmon and shrimp) every day for 1-4 months doesn't seem to make wrinkles noticeably shallower in middle-aged people, according to research that combined results from multiple clinical trials.
See the scientific wording
Oral astaxanthin supplementation (2-12 mg/day for 4-16 weeks) does NOT significantly reduce wrinkle depth in middle-aged adults (SMD = -0.26, 95% CI: -0.58 to 0.06, p=0.11), based on pooled analysis of randomized controlled trials
What the research says
1 studyStudy: Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing
This study tested whether taking astaxanthin pills by mouth helps reduce wrinkles. The results show that astaxanthin did NOT significantly reduce wrinkle depth (the study found the same statistics the claim mentioned: SMD = -0.26, p=0.11). This means the study SUPPORTS the claim that oral astaxanthin doesn't significantly reduce wrinkles.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.